Two studies found that women with no history of depression may be at an increased risk of new onset depressive symptoms and disorders as they transition to menopause.

Although the transition to menopause has long been considered a time of increased risk for developing depressive symptoms, there is little scientific evidence to connect the change in reproductive hormones, menopausal status and mental health.

Ellen W. Freeman, from the University of Pennsylvania School of Medicine, Philadelphia, and colleagues evaluated data from 231 premenopausal women who had no history of depression at the start of the study.

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