Women whose mothers took a common pregnancy drug are at risk of early menopause, research shows. A study of thousands of women revealed that those who were exposed to the ‘wonder drug’ DES in the womb were 50 per cent more likely to start the menopause early.

The discovery adds to the horrific legacy of the anti-miscarriage drug, which has already been linked to a string of health problems.

The mothers-to-be who took it are at increased risk of breast cancer, and research published last week revealed the deadly legacy has been passed onto the daughters, who have double the risk of the disease.

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